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目的:了解徐州市脑卒中流行现状及其危险因素。方法:2017年10月至2018年7月，采用多阶段整群随机抽样方法，抽取徐州市18岁及以上常住居民41 932例，采用问卷收集调查对象一般人口学等信息，体格检查收集身高、体重、血压等信息。采用n χ2检验、趋势n χ2、Logistic回归分析徐州市居民罹患脑卒中可能的危险因素。n 结果:本次共有效调查39 854例，年龄为（52.1±16.8）岁。其中男性19 222例，城市10 323例。脑卒中患者885例，其中男性464例，城市302例。脑卒中患病率为2 220.61/10万，男、女分别为2 413.90/10万、2 040.52/10万，不同性别脑卒中患病率差异有统计学意义（n χ2=6.22，n P=0.013）。城市（2 925.51/10万）高于农村（1 974.20/10万）（n χ2=31.45，n P<0.001）。调整年龄、性别后Logistic回归分析显示，吸烟［1.82（1.53~2.08）］、饮酒［1.22（1.08~1.81）］、睡眠质量［1.42（1.13~1.96）］、体力活动［1.44（1.11~2.14）］、高血压［3.53（2.44~6.02）］、心脏病［1.23（1.11~1.75）］、糖尿病［1.42（1.31~2.05）］、高血压家族史［1.43（1.30~2.37）］、糖尿病家族史［1.22（1.10~1.65）］及脑卒中家族史［1.57（1.46~2.06）］可能是脑卒中的危险因素。Logistic回归分析结果显示，与脑卒中相关的危险因素主要有：年龄［3.02（2.14~4.96）］、吸烟［1.59（1.12~3.85）］、睡眠质量差［1.15（1.03~3.23）］、体力活动缺乏［1.22（1.02~3.23）］、高血压［4.53（3.07~7.36）］、糖尿病［1.08（1.02~3.23）］及脑卒中家族史［1.15（1.08~3.31）］。n 结论:徐州市成年居民脑卒中患病率较高，应根据其危险因素的人群分布特征针对性的开展脑卒中的防控。“,”Objective:To investigate the prevalence and risk factors of stroke in Xuzhou city.Methods:A total of 41 932 residents aged 18 years and above were selected using the multi-stage stratified cluster sampling method. A questionnaire survey was conducted to investigate the rate of stroke, and a physical examination was performed to investigate height, weight, blood pressure, etc. Univariate analyses of stroke were performed using the Chi square test and trend chi-square test. Logistic regression analysis was performed for multi-factor analysis.Results:A total of 39 854 participants (19 222 males, 10 323 from urban areas) from 41 932 eligible participants were included in the statistical analysis, and their average age was (52.1±16.8). In this study, 885 stroke patients (464 males, 302 from urban areas) were found among 39 854 participants. The prevalence of stroke was 2 220.61/100 000, which was separately 2 413.90/100 000 and 2 040.52/100 000 among males and females. The difference between males and females was significant (χ2=6.22, n P=0.013). The prevalence of stroke in urban areas (2 925.51/100 000) was higher than in rural areas (1 974.20/100 000) (χ2n =31.45, n P<0.001). The results of univariate analysis revealed that the risk factors for stroke were [n OR(95%n CI)] smoking [1.82(1.53-2.08)], drinking [1.22(1.08-1.81)], sleep quality [1.42(1.13-1.96)], physical activities [1.44(1.11-2.14)], hypertension [3.53(2.44-6.02)], heart disease [1.23(1.11-1.75)], diabetes [1.42(1.31-2.05)], family history of hypertension [1.43(1.30-2.37)], family history of diabetes [1.22(1.10-1.65)], and family history of stroke [1.57(1.46-2.06)]. Logistic regression analysis showed that age [3.02(2.14-4.96)], smoking [1.59(1.12-3.85)], poor sleep quality [1.15(1.03-3.23)], lack of physical activity [1.22(1.08-3.38)], hypertension [4.53(3.07-7.36)], diabetes [1.08(1.02-3.23)], and family history of stroke [1.15(1.08-3.31)] were related to stroke.n Conclusion:The epidemic of stroke in Xuzhou city was relatively high, and prevention and control measures of stroke should be taken according to the risk factors of stroke in the population distribution.