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目的探讨医院鲍曼不动杆菌临床分布、标本来源及其耐药性。方法回顾性分析医院鲍曼不动杆菌感染患者227例的临床资料。统计分析鲍曼不动杆菌来源、病区分布及耐药性。结果共分离出鲍曼不动杆菌227株,其中分离出最多的科室是ICU,其次是神经内科、神经外科。鲍曼不动杆菌主要来源于痰标本、纤支镜灌洗液、尿液,且均对临床常用抗菌药物有较高的耐药性。鲍曼不动杆菌对氨苄西林/舒巴坦敏感率高于派拉西林/他唑巴坦。结论该院ICU住院患者感染鲍曼不动杆菌的风险最高,且多见耐药菌株。含舒巴坦的β-内酰胺抗菌药物对此类感染有较好疗效。
Objective To investigate the clinical distribution, origin and drug resistance of Acinetobacter baumannii in hospital. Methods The clinical data of 227 cases of Acinetobacter baumannii infection in hospital were retrospectively analyzed. Statistical analysis of Acinetobacter baumannii source, ward distribution and drug resistance. Results A total of 227 Acinetobacter baumannii isolates were isolated, of which ICU was the most separated among them, followed by neurology and neurosurgery. Acinetobacter Bauman mainly from sputum specimens, bronchoscopy lavage fluid, urine, and are commonly used in clinical antimicrobial drugs have high resistance. Acinetobacter baumannii sensitivity to ampicillin / sulbactam than the rate of pyralillin / tazobactam. Conclusion In hospital ICU patients with Acinetobacter baumannii infection the highest risk, and more resistant strains. Sulbactam-containing β-lactam antibiotics have a good effect on such infections.