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一、影响牛黄醒脑注射液1号质量的因素及其质量控制方法牛黄醒脑注射液1号系将安宫牛黄丸中清热解毒的水溶性成份胆酸、α猪脱氧胆酸、水牛角浓缩粉、珍珠母、黄芩、金银花、桅子、板兰根提取制成。即取牛黄中主要有效成份胆酸和α-猪脱氧胆酸,从黄芩中提取黄芩甙,从金银花中提取绿原酸和异绿原酸,从水牛角和珍珠母中水解成多种氨基酸,从板兰根中提取大青素B,从桅子中提取桅子甙,尔后配成牛黄醒脑注射液1号。作为复方注射液,目前存在的主要问题是:
I. Factors Influencing the Quality of Niuhuang Xingnao Injection No. 1 and Its Quality Control Methods Niu Huang Xingnao Injection No. 1 is a water-soluble ingredient that detoxifies and detoxifies the Angong Niuhuang Pills, bile acid, alpha hopodeoxycholic acid, and buffalo horn concentrate Powder, mother-of-pearl, astragalus, honeysuckle, gardenia, and Banlangen are extracted. That is to say, the main active ingredients of bezoar are cholic acid and α-hodactoxycholic acid. Astragalus membranaceus is extracted from Astragalus membranaceus and chlorogenic acid and isochlorogenic acid are extracted from honeysuckle and hydrolyzed into various amino acids from buffalo horn and mother of pearl. Eupatorin B was extracted from Banlangen and Dianzijing was extracted from Dangzi, and then was formulated into Niuhuang Xingnao Injection No. 1. As a compound injection, the major problems that currently exist are: