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目的观察非心源性缺血性脑卒中患者采用双联抗血小板治疗的临床效果。方法选取医院收治的非心源性缺血性脑卒中患者90例作为研究对象,随机分为对照组和观察组,每组45例。对照组予以阿司匹林口服治疗,观察组在对照组基础上实施双联抗血小板法进行治疗。观察2组临床治疗效果及治疗前后血浆黏度、纤维蛋白原、血小板聚集率、全血低切黏度等变化情况。结果观察组总有效率为97.8%,高于对照组的82.2%(P<0.05)。治疗后,2组血浆黏度、纤维蛋白原、血小板聚集率、全血低切黏度水平较治疗前均有所改善,且观察组各项指标优于对照组(P均<0.05)。结论双联抗血小板治疗非心源性缺血性脑卒中的治疗效果较理想,可改善患者的临床症状,保障生活质量,提高患者的生存能力。
Objective To observe the clinical effect of double antiplatelet therapy in patients with non-cardiac ischemic stroke. Methods 90 cases of non-cardiac ischemic stroke admitted to hospital were selected as the research object and randomly divided into control group and observation group, with 45 cases in each group. The control group was treated with aspirin orally, and the observation group was treated with double antiplatelet therapy on the basis of the control group. The clinical curative effect and the change of plasma viscosity, fibrinogen, platelet aggregation rate and whole blood low-cut viscosity before and after treatment were observed. Results The total effective rate in observation group was 97.8%, which was higher than 82.2% in control group (P <0.05). After treatment, the two groups of plasma viscosity, fibrinogen, platelet aggregation rate, low blood viscosity of whole blood were improved than before treatment, and the indicators of the observation group was better than the control group (all P <0.05). Conclusions Dual antiplatelet therapy for non-cardiac ischemic stroke is more effective and can improve the clinical symptoms, ensure the quality of life, and improve the viability of patients.