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目的了解昌平区健康人群风疹、流行性腮腺炎(简称流腮)抗体水平,为传染病控制工作提供科学依据。方法采集昌平区10个村本市及外省人口血标本共220份,采用酶联免疫吸附试验(ELISA)测定风疹、流腮IgG抗体,同时调查风疹、流腮患病史和免疫史及人口学特征。结果 220名调查对象的风疹抗体阳性率为75.00%,其中本市110人抗体阳性率为74.55%,外省110人抗体阳性率为75.45%。风疹IgG抗体浓度均数为64 IU/ml,其中1～4岁年龄组最高,为124 IU/ml。0～1岁年龄组最低,为3 IU/ml;流行性腮腺炎抗体阳性率为80.45%,其中本市110人抗体阳性率为80.91%,外省110人抗体阳性率为80.00%。流腮IgG抗体浓度均数为436 IU/ml。其中20～24岁年龄组最高,为664IU/ml,0～1岁年龄组最低,为122 IU/ml。结论提高麻风腮疫苗基础免疫接种率,在儿童入学前完成1剂加强免疫,对控制风疹和流行性腮腺炎有重要意义。同时应关注成人尤其是育龄期妇女的免疫接种,以减少先天性风疹综合征的发生。
Objective To understand the antibody levels of rubella and mumps in healthy population in Changping District and provide a scientific basis for the control of infectious diseases. Methods Totally 220 blood samples were collected from 10 villages in Changping district and other provinces. The rubella and gungard IgG antibodies were detected by enzyme-linked immunosorbent assay (ELISA), and the history and immunization history of rubella and gonorrhea and demography feature. Results The positive rate of rubella antibody in 220 subjects was 75.00%. The positive rate of 110 human antibodies in this city was 74.55% and the positive rate of 110 human antibodies in other provinces was 75.45%. Rubella IgG antibody concentration was 64 IU / ml, of which the highest age group of 1 to 4 years, 124 IU / ml. The lowest positive rate was 3 IU / ml in 0-1 age group. The positive rate of mumps antibody was 80.45%. The positive rate of 110 human antibodies in this city was 80.91%, and the positive rate of 110 human antibodies in other provinces was 80.00%. The mean concentration of IgG in the gudgeon was 436 IU / ml. Among them, the highest in the 20-24 age group was 664 IU / ml, the lowest in the 0-1 age group was 122 IU / ml. Conclusion It is important to control the rubella and mumps by improving the basic immunization rate of the mumps vaccine and completing one dose of booster immunization before children enroll in the school. At the same time, attention should be paid to the immunization of adults, especially women of childbearing age, so as to reduce the occurrence of congenital rubella syndrome.