长期以来人们就已认识到葡萄糖耐量异常、超重、异常脂蛋白血症和高血压可同时发生。60年代Mehnert形象地将其描述为“富贵综合征”,Hanefeld等提出“代谢综合征”这一概念,并明确指出了本综合征与动脉硬化相关联,美国糖尿病学家Reaven认为胰岛素抵抗是这一包括高血糖、脂质代谢异常、高胰岛素血症和高血压在内的物质代谢综合征的基 It has long been recognized that impaired glucose tolerance, overweight, dyslipoproteinemia and hypertension can occur simultaneously. Mehnert in 1960s vividly described it as “rich syndrome”. Hanefeld et al. Proposed the concept of “metabolic syndrome” and clearly pointed out that this syndrome is associated with atherosclerosis. Reaven, an American diabetic scientist, thinks that insulin resistance is the A substance-based metabolic syndrome that includes hyperglycemia, dyslipidemia, hyperinsulinemia and hypertension