贯叶金丝桃粗提物的黄酮部位在强迫动物游泳实验(FST)中显示明显抗抑郁活性,该部位含金丝桃苷和异槲皮苷等。罗布麻Apocynum venetum L.叶水醇提取物含2.1％金丝桃苷和2.7％异槲皮苷,因而作者采用FST研究了该提取物的抗抑郁作用及活性成分。在急性给药方式实验中,40只雄性CD大鼠分为5组,第1组为对照组,服用去离子水,第2组口服丙咪嗪30mg/kg,第3～5组分别口服125、250和500mg/kg的罗布麻 The flavonoids of Hypericum perforatum crude extract showed significant antidepressant activity in the forced animal swimming test (FST). This site contained hyperin and isoquercitrin. Apocynum venetum L. leaves aqueous alcohol extract contains 2.1% hyperoside and 2.7% isoquercitrin, so the authors used FST to study the antidepressant effects and active ingredients of the extract. In the acute administration experiment, 40 male CD rats were divided into 5 groups. The first group was the control group and was treated with deionized water. The second group was treated with imipramine 30 mg/kg, and the third group was administered orally separately. , 250 and 500 mg/kg of Apocynum