Loeffler综合证是人体对多种过敏原所致的肺部一过性、游走性炎性病变,伴有血嗜酸粒细胞升高。1932年,Loeffler首先报告了51例伴有一过性周围血嗜酸粒细胞增多(0.1～0.3),并有游走性肺部浸润的病例。这些病人大多不伴有呼吸道症状,并在一个月左右自行痊愈。后来即将具有上述特征的病例称为Loeffler综合证。近年来,我们收治本征16例,兹结合文献作一简介。 临床资料 16例中,男11例,女5例,年龄13～52岁,平均31.5岁。本组13例有发病诱因,包括蛔虫3例;氨苄青霉素和花粉症各2例;青霉素、PAS、阿斯匹林、复方新诺明、钩虫及食蟹各1例。主要症状为咳嗽、胸闷、咳少量粘液性痰、发热、乏力等;个别病人有胸痛、畏寒、头痛、食欲不振及皮肤瘙痒等。1例伴有哮喘发作。多数病人缺乏明显的肺部体征,少数可闻及干性啰音。16 Loeffler syndrome is the human body caused by a variety of allergenic lung transient, migratory inflammatory lesions, accompanied by increased blood eosinophils. In 1932, Loeffler first reported 51 patients with transient peripheral blood eosinophilia (0.1-0.3) with migratory pulmonary infiltrates. Most of these patients are not associated with respiratory symptoms and self-healing within a month or so. Later, the case with the above characteristics will be called Loeffler syndrome. In recent years, we treated 16 cases of intrinsic, combined with literature for a brief introduction. Clinical data of 16 cases, 11 males and 5 females, aged 13 to 52 years, mean 31.5 years old. The group of 13 cases of incentive, including roundworm 3 cases; ampicillin and hay fever in 2 cases; penicillin, PAS, aspirin, cotrimoxazole, hookworm and crab in 1 case. The main symptoms of cough, chest tightness, cough and a small amount of mucus phlegm, fever, fatigue, etc .; individual patients have chest pain, chills, headache, loss of appetite and skin itching. 1 case with asthma attack. Most patients lack significant lung signs, a few can be heard and dry rales. 16