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目的调查医院神经内科苦碟子注射液的使用情况,为临床合理使用苦碟了注射液提供参考。方法利用Excel软件对医院神经内科2013年上半年使用苦碟子注射液208例的适应证、用法用量、疗程、溶媒、联合用药及不良反应进行统计分析。结果神经内科苦碟子注射液主要用于脑梗死(使用率48.08%)、椎基底动脉供血不足或短暂性供血不足(使用率16.35%)、神经症(使用率9.13%)、脑炎(使用率7.21%)等;用药浓度>10ml/100ml的占97.60%,而用药浓度≤10ml/100ml只占2.40%;用药疗程<14d的占76.44%,用药疗程=14d的占3.37%,用药疗程>14d的占20.19%;无不当联用药物;2例出现了不良反应,占0.96%。结论神经内科使用苦碟子注射液基本合理,主要存在问题为输液溶媒用量偏小,导致药物浓度偏高,少数存在超说明书用药问题。
Objective To investigate the use of Kudiezi Injection in Department of Neurology of the Hospital and provide a reference for clinical use of Kudie Injection. Methods The software of Excel was used to analyze the indications, dosages, courses of treatment, solvent, combination therapy and adverse reactions of 208 cases of Kudiezi injection in the first half of 2013 in the department of neurology of the hospital. Results Neurology Kupiezi injection was mainly used in cerebral infarction (48.08%), vertebrobasilar insufficiency or transient hypoperfusion (usage rate 16.35%), neurosis (usage rate 9.13%), encephalitis 7.21%). Drug concentration> 10ml / 100ml accounted for 97.60%, while drug concentration ≤10ml / 100ml only accounted for 2.40%; medication course 14d accounted for 76.44%, medication course = 14d accounted for 3.37% Accounted for 20.19%; no inappropriate combination of drugs; 2 cases of adverse reactions, accounting for 0.96%. Conclusion Neurology, Kodie injection is basically reasonable, the main problems are the amount of infusion solution is too small, leading to high drug concentrations, there are a few super-manual drug problems.