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目的 对 17例病理组织学证实的转移性肿瘤患者进行18氟 脱氧葡萄糖 (18F DG)PET全身显像 ,以评价其在寻找原发灶中的价值。方法 所有患者均进行18F DGPET全身显像 ,结果判断应用目测法和半定量分析方法 (标准摄取值 ,SUV)。结果 17例患者中 ,12例PET可检出原发灶 (70 .6 % ) ,其中肺癌 9例 ,鼻咽癌 2例 ,乳腺癌 1例。常规显像检查只有 6例发现原发灶 (35 .3 % )。 5例原发灶不明者 ,临床随访 2～ 10个月 ,1例证实为前列腺癌 ,余 4例临床随访未见原发灶。 17例患者中 8例PET检出了常规显像检查未能发现的其他转移灶。结论 对转移瘤患者进行全身PET检查有助于原发灶的寻找 ,尤其是临床上原发灶不明者 ,PET一次检查可了解肿瘤原发灶及全身转移情况 ,包括骨骼及软组织的转移 ,为临床制订治疗方案提供可靠依据
Objective To evaluate the value of 18F DG PET whole body imaging in 17 cases of histopathologically proven metastatic tumors in order to evaluate their value in the search for primary lesions. Methods All patients underwent 18F DGPET whole-body imaging. The results were judged using visual and semi-quantitative methods (standard uptake values, SUV). Results Of the 17 patients, primary lesions were detected in 12 cases of PET (70.6 %), including 9 cases of lung cancer, 2 cases of nasopharyngeal carcinoma, and 1 case of breast cancer. Only 6 primary lesions (35.3%) were found in routine imaging examinations. 5 cases of primary lesions were unknown, clinical follow-up of 2 to 10 months, 1 demonstrated prostate cancer, and the remaining 4 patients had no primary lesions during clinical follow-up. In 8 of the 17 patients, PET detected other metastases that could not be detected by conventional imaging. Conclusions Whole-body PET examination of patients with metastatic tumors is helpful for the search of primary lesions. In particular, primary PET imaging can be used to understand the primary tumor and systemic metastases, including bone and soft tissue metastasis. Establishing a clinical treatment plan provides a reliable basis