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目的研究Monaco治疗计划系统中不同参数设置对容积旋转调强放射治疗(VMAT)计划质量的影响,得出更合理的治疗计划参数设置以提高VMAT治疗质量。方法 2010年15月间治疗3例患者,为食管癌、宫颈癌和鼻咽癌各1例,分别设置不同的计划参数进行容积旋转调强计划优化,通过多种评估指标比较各VMAT计划质量的差异,得出临床所需的MSC、MSS、SSF、Sm、MMS和MDR共6个治疗计划参数对VMAT治疗质量的影响。结果 MSC、MSS和SSF的3个参数对VMAT治疗质量不产生影响,有影响的Sm、MMS和MDR参数中,随着Sm和MMS值的增大,VMAT计划的剂量分布逐渐变差,但控制点数、机器跳数和照射时间均逐渐减小;随着MDR值增大,VMAT治疗的剂量分布先逐渐变差后不变,控制点数和机器跳数均是先增大后不变,而照射时间是先减小后不变。结论 Sm、MMS和MDR3个参数对VMAT计划质量有较大影响,对不同的患者,设置合适的Sm、MMS和MDR值对提高计划质量非常重要。
Objective To study the influence of different parameter settings in Monaco treatment planning system on the quality of Volume Rotating Intensity Modulated Radiation Therapy (VMAT), and to obtain more reasonable treatment planning parameters to improve the quality of VMAT. Methods Three patients were treated in December 2010 for esophageal cancer, cervical cancer and nasopharyngeal carcinoma in one case. Different planning parameters were set for optimization of volume rotation intensity modulation plan, and the quality of each VMAT plan was compared through various evaluation indexes Differences were analyzed to determine the effect of six treatment planning parameters, including MSC, MSS, SSF, Sm, MMS and MDR, on the quality of VMAT. Results The three parameters of MSC, MSS and SSF had no effect on the quality of VMAT treatment. In Sm, MMS and MDR parameters, the dose distribution of VMAT decreased with the increase of Sm and MMS, but the control The number of hops, the number of machine hops and irradiation time decreased gradually. With the increase of MDR value, the dose distribution of VMAT did not change after the dose distribution gradually decreased. The control points and machine hops increased first and then unchanged, Time is the first to reduce the same. Conclusion The three parameters of Sm, MMS and MDR have a significant impact on the quality of VMAT plan. Setting appropriate values of Sm, MMS and MDR for different patients is very important to improve the quality of plan.