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本文报告34例睾丸精原细胞瘤术后深部X线或~(60)钴放射治疗,疗后随访3~10年以上,3年生存率88.2%(30/34),5年生存率85.7%(24/28)。复习文献认为对Ⅰ期单纯精原细胞瘤只需照射同侧髂区和腹主动脉旁淋巴区。对Ⅱ、Ⅲ期则应加照射纵隔和左锁骨上区。选择性照射剂量2,500rad是适宜量,对小的至中等大的转移灶照射2,500~3,500rad,对腹膜后大块病灶先行全腹照射,随后缩小放射野对残留瘤块追加照射1,000~1,500rad,以使肿瘤完全消退,对晚期病例应用化疗与放射综合治疗是有益的。
This article reports 34 cases of testicular seminoma postoperative deep X-ray or ~ (60) cobalt radiation therapy, follow-up of 3 to 10 years after treatment, 3-year survival rate of 88.2% (30/34), 5-year survival rate of 85.7% (24/28). The review literature suggests that for stage I pure seminoma, only the ipsilateral diaphragm area and the paraaortic lymph node area need only be irradiated. Stage II and III should be irradiated with mediastinum and left supraclavicular area. The selective irradiation dose of 2,500 rad was suitable, and the small to medium-sized metastases were irradiated with 2,500 to 3,500 rad. The retroperitoneal mass lesions were irradiated in the entire abdomen, and then the radiation field was reduced. The additional irradiation of the residual tumor mass was 1,000 to 1,500 rad. In order to complete regression of the tumor, it is beneficial to use advanced chemotherapy and radiation therapy in advanced cases.