生长抑素是在下丘脑正中隆起、大脑皮层、脑干、脊髓以及感觉神经节、胰腺D细胞、甲状腺C细胞、胃肠的许多内分泌细胞中合成的14肽单链激素,对多种内分泌及腺体有抑制作用。近年来已有其人工合成的8肽衍生物,使生长抑素在临床得到广泛应用,对上消化道出血、倾倒综合征、胰腺炎、糖尿病、肢端肥大症、肠梗阻等疾病有一定疗效,副作用轻而少见。 Somatostatin is a 14-mer single-stranded hormone synthesized in many endocrine cells of the hypothalamus, the cerebral cortex, the brain stem, the spinal cord and the sensory ganglia, the pancreatic D cells, the thyroid C cells, and the gastrointestinal tract. Body inhibitory effect. In recent years, 8-peptide derivatives have been synthesized, so that somatostatin is widely used clinically and has some effects on diseases such as upper gastrointestinal bleeding, dumping syndrome, pancreatitis, diabetes, acromegaly and intestinal obstruction Side effects are light and rare.