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目的探讨和分析急性冠状动脉综合征介入术前应用他汀类药物强化治疗的临床疗效,总结其临床价值。方法回顾性分析具有完整临床资料的2008年10月至2010年10月来我院就诊的急性冠状动脉患者100例,随机分为观察组和对照组两组,每组患者有50例,对照组进行常规的药物支架治疗,观察组在对照组治疗的基础上在术前给予他汀类药物强化治疗,观察和比较两组不同治疗方法对急性冠状动脉综合征的临床疗效。结果经统计学检验,观察组和对照组两组术前的C反应蛋白水平差异无统计学意义(P>0.05),术后两组患者的C反应蛋白水平差异有统计学意义(P<0.05)。两组患者术前血脂水平差异无统计学意义(P>0.05),术后两组患者的血脂水平差异有统计学意义(P<0.05),观察组疗效优于对照组。结论急性冠状动脉综合征介入术前应用他汀类药物强化治疗疗效显著安全可靠,是急性冠状动脉综合征的有效方法之一,具有较好的临床价值,值得临床推广和应用。
Objective To investigate and analyze the clinical efficacy of intensive statin therapy before PCI in patients with acute coronary syndrome and to summarize its clinical value. Methods A retrospective analysis of 100 patients with acute coronary syndrome who came to our hospital from October 2008 to October 2010 with complete clinical data was randomly divided into observation group and control group, with 50 cases in each group and control group The patients in the observation group were given statin intensive therapy on the basis of the treatment of the control group. The clinical efficacy of two different treatment methods on acute coronary syndrome was observed and compared. Results There was no significant difference in preoperative C-reactive protein levels between the observation group and the control group (P> 0.05). There was significant difference in C-reactive protein between the two groups after operation (P <0.05 ). There was no significant difference in preoperative blood lipid levels between the two groups (P> 0.05). There was significant difference in the level of blood lipid between the two groups after operation (P <0.05). The curative effect of the observation group was better than that of the control group. Conclusion It is safe and reliable to use statins to strengthen the treatment before acute coronary syndrome. It is one of the effective methods of acute coronary syndrome. It has good clinical value and is worthy of clinical promotion and application.