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目的:观察哺乳妇女口服吲哚美辛对婴儿生理性腹泻的影响。方法:将123例生理性腹泻婴儿母子配对,分为治疗组65例,对照组58例,治疗组乳母口服吲哚美辛25mg,每日2次,10日为1疗程,对照组乳母口服安慰剂维生素C,疗程同前。同时测定治疗前后母乳地诺前列酮的含量。结果:治疗组总有效率为95%,母乳地诺前列酮含量明显降低,对照组总有效率为2%,母乳地诺前列酮含量无明显变化。两组比较有统计学差异,P<0.001。结论:乳母口服吲哚美辛治疗婴儿生理性腹泻疗效显著。
Objective: To observe the effect of oral indomethacin on physiological diarrhea in lactating women. Methods: 123 pairs of physiological diarrhea infants and mothers were paired, divided into treatment group 65 cases, 58 cases of control group, the treatment group breast numbness oral indomethacin 25mg, 2 times a day, 10 days for a course of treatment, the control group of maternal oral comfort Agent vitamin C, treatment with the previous. At the same time, the content of noprilone in breast milk before and after treatment was measured. Results: The total effective rate was 95% in the treatment group, the content of Norfopressone in breast milk was significantly decreased, the total effective rate in the control group was 2%, and the content of norprostone in breast milk did not change significantly. There was a significant difference between the two groups, P <0.001. Conclusion: The efficacy of indomethacin in infants with oral diarrhea is obvious.