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氟嗪酸是一种新型氟喹诺酮类广谱抗生素,对革兰阳性、革兰阴性菌有效,对淋球菌、沙眼衣原体和结核杆菌赤有作用。近年来发现,耐利福平和耐乙胺丁醇的结核菌逐渐增多,给复治带来困难。我院自1988年以来,将氟嗪酸与二种该病例未曾用过的抗痨药联合应用,治疗难治性肺结核13例,近期疗效满意。难治性肺结核的诊断标准:(1)复治患者,痰菌长期持续或断续阳性,并对大部分抗结核药物耐药者,长期咳嗽多痰,反复咯血或痰血、气短,胸片示两侧广泛纤维干
Olanzapine is a new fluoroquinolone broad-spectrum antibiotic that is effective against Gram-positive, Gram-negative bacteria and has a role in Neisseria gonorrhoeae, Chlamydia trachomatis and Mycobacterium tuberculosis. In recent years, it has been found that tuberculosis resistant to rifampicin and ethambutol gradually increased, which made it difficult for retreatment. In our hospital since 1988, the combination of fluazic acid and two anti-tubercular drugs which have not been used in this case, 13 cases of refractory pulmonary tuberculosis have been treated in our hospital, and the short-term curative effect is satisfactory. Diagnostic criteria for refractory tuberculosis: (1) retreatment patients, sputum bacteria continuous or intermittent positive for most of the anti-tuberculosis drug-resistant persons, long-term cough and phlegm, repeated hemoptysis or sputum, shortness of breath, chest X-ray Show extensive fiber dry on both sides