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目的:本文旨在探讨中华麦饭石防治大鼠肝炎、肝硬化和肝癌时微量元素的作用方法:给wistar大鼠食用二甲基奶油黄饲料,同时饮用10%中华麦饭石浸液共26周。用ICP法检测肝炎、肝硬化和肝癌大鼠全血10种微量元素。结果:肝炎时实验组仅Mn显著高于对照组(P<005)。肝硬化时实验组Mn、Si、Ba、Fe、Zn和Se均显著高于对照组,Cu显著低于对照组(P<005~0.001)。肝癌时实验组Mn、Si、Ba、Fe、Zn、Se和Mo继续高于对照组,Cu和Cr低于对照组(P<0001)。除Si外,实验组和正常对照组微量元素差异无显著意义(P<005)。结论:1肝病越重,微量元素变化越明显。2中华麦饭石能维持机体微量元素的正常状态,对大鼠肝炎、肝硬化和肝癌防治具有重要作用。
Objective: The purpose of this article is to explore the role of Chinese medical stone in the prevention and treatment of hepatitis, cirrhosis and hepatocellular carcinoma in rats Methods: The wistar rats were given dimethyl butter yellow feed, while drinking 10% Chinese medical stone immersion total 26 week. Detection of 10 Trace Elements in Whole Blood of Hepatitis, Cirrhosis and Liver Cancer with ICP Method. Results: Only Mn in experimental group was significantly higher than that in control group (P <005). The levels of Mn, Si, Ba, Fe, Zn and Se in cirrhosis group were significantly higher than those in control group, and Cu was significantly lower than that in control group (P <005 ~ 0.001). The contents of Mn, Si, Ba, Fe, Zn, Se and Mo in the experimental group were higher than those in the control group, while the contents of Cu and Cr in the liver cancer group were lower than those in the control group (P <0001). In addition to Si, the experimental group and the normal control group no significant difference in trace elements (P <0 05). Conclusions: 1 more severe liver disease, the more obvious changes in trace elements. 2 Chinese medical stone can maintain the body’s normal state of trace elements on rat hepatitis, cirrhosis and prevention and treatment of liver cancer has an important role.