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人们曾用枸橼酸克罗米芬(CC)治疗精子参数异常的男子。目前对治疗效果有争论。一些报告认为用药后可增加精于数量,另一研究认为可提高多数病人的精子活动力。也有研究认为用常规剂量25mg/天不提高精子的活力,但每隔一天给25mg的低剂量可提高精子的活力,其它一些研究则认为用CC对提高精于的数量和活力没有重要意义。现用Kruger等出提的新标准检测精子形态以预测体外受精(IVF)的结果,并评价给与CC时间的长短对精子形态的影响。低于正常精子密度(>10×10~6/ml)的74名男子为试验组,禁欲48~72小时后取精液标本,用计算机分析精液。每月连续给CC25天,25mg/天或
Men have been treated with clomiphene citrate (CC) for abnormal sperm parameters. The current controversial treatment effect. Some report that the amount of medication can be increased after finishing, another study that can increase the sperm motility in most patients. There are also studies suggest that the conventional dose of 25mg / day does not increase sperm motility, but every other day to give a low dose of 25mg can increase sperm motility, while others believe that the use of CC to improve the quality and quantity of vitality is not important. The new criteria, now used by Kruger et al., Test the morphology of the sperm to predict the outcome of in vitro fertilization (IVF) and evaluate the effect of given CC duration on sperm morphology. Seventy-four men who were below normal sperm density (> 10 × 10 ~ 6 / ml) were included in the test group. Semen samples were taken after 48 to 72 hours of abstinence and seminal fluid was analyzed by computer. Continuous to CC25 days a month, 25mg / day or