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目的 探讨小儿重症肺炎肾血流动力学变化的临床意义。方法 应用彩色多普勒测定 38例小儿重症肺炎急性期和恢复期及 2 4例正常对照组肾血流动力学变化。结果 小儿重症肺炎急性期肾主动脉及各分支收缩期峰值血流速度 (Vmax)、舒张末期血流速度 (Vmin)均显著下降 (P <0 0 1) ,阻力指数 (RI)、搏动指数 (PI)明显升高 (P <0 0 1) ,恢复期与对照组各项测定值比较无显著差异。结论 肾脏血流动力学的病理变化是小儿重症肺炎肾脏损害和功能障碍的重要原因 ,给予临床干预可恢复正常。彩色多普勒测定肾血流变化可用于重症肺炎患儿肾脏损害的早期诊断及指导治疗
Objective To investigate the clinical significance of hemodynamic changes in severe pneumonia in children. Methods The color Doppler was used to measure the changes of renal hemodynamics in 38 cases of severe pneumonia in acute and convalescent stage and in 24 normal controls. Results In the acute stage of pediatric severe pneumonia, the peak velocity of Vmax and Vmin of the renal artery and its branches decreased significantly (P <0.01), the resistance index (RI), the pulsatility index PI) was significantly higher (P <0.01), convalescent period compared with the control group did not show any significant difference. Conclusion The pathological changes of renal hemodynamics is an important cause of kidney damage and dysfunction in children with severe pneumonia. The clinical intervention may return to normal. Color Doppler measurement of renal blood flow changes can be used for early diagnosis and treatment of kidney damage in children with severe pneumonia