为诱导实验性、地方性、缺碘性甲状腺肿和克汀病的动物模型,研制成功丁 GR—2号低碘饲料。鼠经3月饲养后发现:实验动物甲状腺增生、重量和体积明显增加,滤泡增多;血清 T_4值显著下降。结果表明:该饲料是复制缺碘性甲状腺肿和地方性克汀病动物模型的理想低碘饲料。 To induce experimental, endemic, iodine-deficient goiter and cretinism in animal models, the successful development of GR-2 low iodine feed. Rats raised in March found: experimental animals, thyroid hyperplasia, weight and volume increased significantly, increased follicles; serum T_4 value decreased significantly. The results showed that the feed was an ideal low-iodine feed for replicating animal models of iodine deficiency goiter and endemic cretinism.