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抽动障碍是儿童时期常见的神经精神障碍,病因和病理机制不明,近年来认为,链球菌感染是其遗传易患性升高的环境因素,某些患儿发病与链球菌感染后自身免疫反应密切相关,其血清中抗链球菌抗体滴度升高,并可检测到抗神经元抗体,推测是链球菌抗原与脑组织有交叉免疫反应,D8/17被认为是神经精神疾病的标志。与A族链球菌感染有关的自身免疫性神经精神障碍为一新的诊断名词,静脉内免疫球蛋白为一些难治性抽动障碍患者的治疗提供了新的思路。
Tic disorder is a common childhood neuropsychiatric disorders, the etiology and pathology unknown, in recent years that the streptococcal infection is an increased genetic predisposition to environmental factors, some children with autoimmune reactions after streptococcal infection and close Related serum anti-streptococcal antibody titers increased, and anti-neuronal antibodies can be detected presumed to be cross-immunized with streptococcal antigens and brain tissue. D8 / 17 is considered as a hallmark of neuropsychiatric disorders. A group of Streptococcus group A autoimmune neuropsychiatric disorders as a new diagnostic term, intravenous immunoglobulin for some refractory tic dysfunction in patients with treatment provides a new way of thinking.