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目的 :探讨外周血活化T淋巴细胞含量和血清sIL -2R水平对于恶性肿瘤诊断的临床价值。方法 :应用流式细胞免疫学方法、酶联免疫试剂盒ELISA法对 45例恶性肿瘤患者外周血活化T细胞、血清sIL -2R水平分别进行定量测定。结果 :恶性肿瘤患者外周血活化T细胞含量和血清sIL -2R水平均明显高于正常对照组 ;活化T细胞含量与血清sIL -2R水平呈明显相关性 (r =0 .76 12 ,P <0 .0 5 )。结论 :活化T细胞含量和血清sIL -2R水平与肿瘤的恶性增生、进展有一定关系 ,可作为恶性肿瘤免疫诊断的重要指标
Objective : To investigate the clinical value of peripheral blood activated T lymphocyte and serum sIL-2R levels in the diagnosis of malignant tumors. Methods: The levels of activated T cells and serum sIL-2R in peripheral blood of 45 patients with malignant tumors were determined by flow cytometric immunoassay and enzyme-linked immunosorbent assay (ELISA). Results: The levels of activated T cells and serum sIL-2R levels in peripheral blood of patients with malignant tumors were significantly higher than those in normal controls; the levels of activated T cells were significantly correlated with serum sIL-2R levels (r = 0.716, P < 0). .0 5 ). Conclusion : The level of activated T cells and serum sIL-2R levels are related to the malignant proliferation and progression of tumors. It can be used as an important indicator for the diagnosis of malignant tumors.