目的比较子宫肌瘤剥除术、行子宫全切术对子宫肌瘤患者内分泌功能及性功能的影响。方法选取子宫肌瘤患者80例,其中30例患者行子宫肌瘤剥除术为A组,25例行子宫全切或次全切保留双附件为B组,25例行子宫全切、双附件切除为C组。比较切除前、后子宫肌瘤剥除术行子宫全切术对子宫肌瘤患者内分泌功能及性功能的影响,并对所有患者术后随访1年。结果 3组患者手术前各项激素水平、性功能差异无统计学意义(P>0.05);A组手术后8周、24周与手术前相比各激素水平、性功能差异无统计学意义(P>0.05);B组手术后8周与手术前相比各激素水平差异无统计学意义(P>0.05),手术后24周与手术前相比差异有统计学意义(P<0.05);C组手术后8周、24周与手术前相比各激素水平差异均有统计学意义(P<0.05);B组手术后8周、24周与手术前相比性心理差异有统计学意义(P<0.05),其他性功能指标差异无统计学意义(P>0.05);C组手术后8周、24周与手术前相比性唤起差异无统计学意义(P>0.05),其他性功能指标差异有统计学意义(P<0.05)。随访1年,3组围绝经期症状的发生率分别为10.00%、24.00%、83.00%,差异有统计学意义(P<0.05)。结论要根据患者的不同需求选择手术方式,子宫肌瘤剔除手术对患者内分泌功能及性功能影响较小。 Objective To compare the effects of hysterectomy and hysterectomy on endocrine function and sexual function in patients with uterine fibroids. Methods Totally 80 patients with uterine myoma were enrolled. Thirty patients underwent myomectomy for group A, 25 patients underwent total hysterectomy or subtotal resection with group B, 25 patients underwent hysterectomy and double attachment C group was excised. Comparison of hysterectomy before and after hysterectomy hysterectomy on endocrine function and sexual function in patients with uterine fibroids, and all patients were followed up for 1 year. Results There were no significant differences in the levels of hormones and sexual functions between the three groups before surgery (P> 0.05). There was no significant difference in the levels of hormones and sexual functions between groups A and B at weeks 8 and 24 after surgery There was no significant difference in the levels of hormones between the two groups at 8 weeks after operation (P> 0.05). There was a significant difference between the two groups at postoperative 24 weeks and before operation (P <0.05). There were significant differences in the levels of hormones between the 8th week and the 24th week after operation in group C (P <0.05), and there was significant difference in the psychological state between the 8th week and the 24th week after operation (P <0.05). There was no significant difference in other sexual function indexes between the two groups (P> 0.05). There was no significant difference in evoked echocardiography between 8 and 24 weeks after operation in group C (P> 0.05) The difference of functional indexes was statistically significant (P <0.05). The follow-up of 1 year, the incidence of perimenopausal symptoms in 3 groups were 10.00%, 24.00%, 83.00% respectively, the difference was statistically significant (P <0.05). Conclusion According to the different needs of patients choose surgical methods, myomectomy surgery on patients with endocrine function and sexual function less affected.