肿瘤标志物(tumor marker,TM)是指在肿瘤的发生和增殖过程中,由肿瘤细胞本身所产生的或者是由机体对肿瘤细胞反应而产生的,反映肿瘤存在和生长的一类物质,包括蛋白质、激素、酶、多胺及癌基因产物等。肿瘤标志物在肿瘤普查、诊断、判断预后、评价疗效和高危人群随访观察等方面都具有较大的实用价值。目前,对血清中肿瘤标志物的检测免疫分析法,将生物化学、核医学、免疫学、细胞学、病理学、分子生物学等诸多学科融合在一起。 Tumor marker (TM) refers to a class of substances that are produced by the tumor cells themselves or react with the tumor cells during tumorigenesis and proliferation and reflect the existence and growth of the tumor, including Proteins, hormones, enzymes, polyamines and oncogene products. Tumor markers in the tumor screening, diagnosis, prognosis, evaluation of efficacy and follow-up observation of high-risk groups have a greater practical value. At present, the detection of serum tumor markers immunoassay, biochemistry, nuclear medicine, immunology, cytology, pathology, molecular biology and many other disciplines together.