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在广西梧州市进行了鼻咽癌的血清学普查,从年龄为40~59的居民12932人采血。VCA/IgA抗体的阳性率为5.3%,EA/IgA抗体的阳性率为VCA/IgA抗体阳性者的4.4%。VCA/IgA抗体阴性者的EA/IgA抗体也是阴性。从VCA/IgA抗体阳性者中检查出13例鼻咽癌,其中9例的EA/IgA抗体也是阳性。12932人群中的鼻咽癌检出率为100.5/10万,VCA/IgA抗体阳性者的鼻咽癌检出率为1900/10万,分别较1975—1978年同年龄组人群的年发病率高一倍和37倍。这些结果进一步证明EB病毒与鼻咽癌关系密切。13例鼻咽癌中Ⅰ期9例,占70%,Ⅱ期4例,占30%。因此,早期诊断和早期治疗可以降低病死率。
A serological survey of nasopharyngeal carcinoma was conducted in the city of Wuzhou, Guangxi. Blood was collected from 12932 residents aged 40-59. The positive rate of VCA/IgA antibody was 5.3%, and the positive rate of EA/IgA antibody was 4.4% of those positive for VCA/IgA antibody. VCA/IgA antibody negative EA/IgA antibodies were also negative. Thirteen nasopharyngeal carcinomas were detected from patients with positive VCA/IgA antibodies, and 9 of them were positive for EA/IgA antibodies. The detection rate of nasopharyngeal carcinoma in the 12932 population was 100.5 per 100 000. The detection rate of nasopharyngeal carcinoma in patients with positive VCA/IgA antibodies was 1900 per 100 000, which was higher than the annual incidence in the same age group from 1975 to 1978. Doubled and 37 times. These results further prove that EB virus is closely related to nasopharyngeal carcinoma. Among 13 cases of nasopharyngeal carcinoma, 9 cases were in stage I, accounting for 70%, and 4 cases were in stage II, accounting for 30%. Therefore, early diagnosis and early treatment can reduce the mortality rate.