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目的 :研究联合使用氯吡格雷和阿司匹林治疗心肌梗塞的临床效果。方法 :对2013年2月~2014年2月期间我院收治的76例心肌梗塞患者的临床资料进行回顾性研究。我们将这76例患者随机分为阿司匹林组和联合组,每组各有38例患者。我院单独使用阿司匹林对阿司匹林组患者进行治疗,联合使用氯吡格雷和阿司匹林对联合组患者进行治疗。治疗结束后,比较两组患者治疗的效果和不良反应的发生率。结果 :联合组患者治疗的总有效率为97.37%。阿司匹林患者治疗的总有效率为78.95%。联合组患者治疗的总有效率明显高于阿司匹林组患者,二者相比差异具有显著性(P<0.05)。在治疗期间,两组患者不良反应的发生率大体相当,二者相比差异无显著性(P>0.05)。结论 :联合使用氯吡格雷和阿司匹林治疗心肌梗塞的效果确切,而且安全性高。此联合用药方法可作为临床上治疗心肌梗塞的优选方法。
Objective: To study the clinical effect of combined use of clopidogrel and aspirin in the treatment of myocardial infarction. Methods: The clinical data of 76 patients with myocardial infarction admitted to our hospital from February 2013 to February 2014 were retrospectively studied. We randomly assigned 76 patients to the aspirin group and the combined group, each with 38 patients in each group. In our hospital, aspirin alone was used to treat patients in the aspirin group. Patients in the combined group were treated with clopidogrel and aspirin. After treatment, the effect of treatment and the incidence of adverse reactions in both groups were compared. Results: The total effective rate of treatment in combination group was 97.37%. Aspirin treatment of patients with a total effective rate of 78.95%. The total effective rate of treatment in combination group was significantly higher than that in aspirin group, the difference was significant (P <0.05). During the treatment, the incidence of adverse reactions in both groups was roughly the same, with no significant difference between the two groups (P> 0.05). Conclusions: The combination of clopidogrel and aspirin in the treatment of myocardial infarction is effective and safe. This combination therapy can be used as a clinical treatment of myocardial infarction preferred method.