论文部分内容阅读
采用相溶解度法考察了25℃时羟丙基-β-环糊精(HP-β-CD)、乙二胺-β-环糊精(en-β-CD)、二乙烯三胺-β-环糊精(dien-β-CD)对野黄芩素的增溶作用,得到野黄芩素在环糊精及其衍生物中的相溶解度曲线均为AL型,说明其与环糊精的包合比为1:1。结果表明3种环糊精主体化合物对野黄芩素的增溶作用大小为:en-β-CD>dien-β-CD>HP-β-CD。
The solubility of hydroxypropyl-β-cyclodextrin (HP-β-CD), ethylenediamine-β-cyclodextrin (en-β-CD), diethylenetriamine- Cyclodextrin (dien-β-CD) solubilization of baicalein obtained baicalein in cyclodextrins and their derivatives phase solubility curve are AL type, indicating the inclusion of cyclodextrin The ratio is 1: 1. The results showed that the solubility of baicalein in the three cyclodextrins was en-β-CD> dien-β-CD> HP-β-CD.