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出血性休克复苏中,对用液量和时间一直存在着争议。临床资料显示,伤者转送到急救中心前和手术控制出血之前,复苏可以防止伤者死亡。本研究重新评价早期等渗盐水扩容复苏对非麻醉状态下大鼠严重活动性出血时的影响。实验选用63只207～298g雌性SD大鼠,随机均分为三组。A组:不复苏;B组:用40ml/kg等渗盐水复苏(154μmol/L NaCl);C组:80ml/kg的等渗盐水复苏。测量参数,包括收缩压、舒张压、脉压和脉率,数据用方差分析处理,各组的死亡率用卡方图表示。结果显示,在
Hemorrhagic shock recovery, there is always controversy on the amount of fluid and time. Clinical data show that resuscitation can prevent the casualties from being injured before they are forwarded to the emergency center and before surgery to control bleeding. This study reevaluated the effect of early isotonic saline dilatation and resuscitation on severe active bleeding in non-anesthetized rats. Sixty-three 207 ~ 298g female SD rats were randomly divided into three groups. Group A: no resuscitation; Group B: 40ml / kg isotonic saline resuscitation (154μmol / L NaCl); Group C: 80ml / kg isotonic saline resuscitation. Measurement parameters, including systolic pressure, diastolic pressure, pulse pressure and pulse rate, were analyzed using analysis of variance (ANOVA), and the mortality in each group was expressed as a chi-squared graph. The results show that at