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目的分析本院2013—2015年度口服降糖药的应用情况。方法以如东县丰利镇中心卫生院2013—2015年口服降糖药的销售金额、用药频度、日均费用为指标,对抽取的400张含口服降糖药处方的用药方案进行统计分析。结果本院口服降糖药的销售金额逐年上升,临床常用磺酰脲类、噻唑烷二酮类、双胍类降糖药物,其中二甲双胍肠溶胶囊、吡格列酮片、格列美脲片用药频度高,格列吡嗪控释片也应用较好。降餐后血糖为主的格列奈类、α-葡萄糖苷酶抑制剂由于价格偏贵,临床应用始终受到局限。结论 2013—2015年度本院口服降糖药的应用基本合理,但要对照《中国2型糖尿病防治指南(2013版)》,进一步提高双胍类的应用,尤其是单药治疗的首选。同时临床应参照指南为患者选择安全、有效、经济、合理的口服降糖药。
Objective To analyze the application of oral hypoglycemic agents in our hospital from 2013 to 2015. Methods Taking the sales amount, frequency of medication and daily average cost of oral hypoglycemic agents in Fengli Town Central Hospital of Rudong from 2013 to 2015 as the index, the statistic analysis of 400 prescriptions containing oral hypoglycemic agents . Results The sales amount of oral hypoglycemic agents increased year by year. Commonly used sulfonylureas, thiazolidinediones and biguanides hypoglycemic drugs, metformin enteric-coated capsules, pioglitazone tablets and glimepiride tablets were frequently used , Glipizide controlled release tablets are also better. After meals blood glucose-based glinides, α-glucosidase inhibitors due to the price of your side, the clinical application has always been limited. Conclusion The application of oral hypoglycemic agents in our hospital is reasonable in 2013-2015. However, the guidelines for the prevention and treatment of type 2 diabetes in China (2013 version) should be compared with those in 2013-2015 to further improve the application of the biguanides, especially for monotherapy. At the same time should refer to the guidelines for clinical patients choose safe, effective, economical and reasonable oral hypoglycemic agents.