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目的分析2012年-2013年本辖区腹泻患者中沙门菌的感染情况及耐药特征,为防治沙门菌感染和临床治疗提供依据。方法采用GB 4789.4—2010沙门菌检测方法,对从腹泻患者中分离的49株沙门菌进行分离鉴定,阳性菌株用全自动细菌鉴定仪做生化鉴定及药敏分析。结果沙门菌感染主要以幼年组(0岁~5岁)儿童为主,分离高峰集中在春季、夏季;鼠伤寒沙门菌的分离率最高,菌株对青霉素类及磺胺类药物耐药率较高,存在多重耐药菌株。结论鼠伤寒沙门菌是本辖区感染性腹泻的优势菌型,感染患者的年龄呈现低龄化,沙门菌耐药率呈逐年升高趋势,菌株多重耐药形势严峻。
Objective To analyze the infection status and drug resistance of Salmonella in patients with diarrhea in this area from 2012 to 2013 and provide basis for the prevention and treatment of Salmonella infection and clinical treatment. Methods Salmonella typhimurium (GB 4789.4-2010) was used to isolate and identify 49 strains of Salmonella isolated from patients with diarrhea. The positive strains were identified by biochemical identification and drug susceptibility analysis using an automatic bacterial analyzer. Results Salmonella infection mainly occurred in children (0 to 5 years old). The peak of separation was concentrated in spring and summer. The isolation rate of Salmonella typhimurium was the highest, and the strains were resistant to penicillins and sulfonamides. There are multiple drug-resistant strains. Conclusions Salmonella typhimurium is the predominant bacterial strain of infectious diarrhea in this area. The age of infected patients is younger, the rate of Salmonella increased year by year, and the multi-drug resistance of strains is severe.