患者女 ,4 6岁。因左耳闷、重听伴左侧耳鸣 2月来诊。患者因症状渐进性加重伴头痛在当地医院就诊 ,见左耳骨室积液 ,2次鼓膜穿刺淡黄色液体 ,检查左侧鼻咽部隆起 ,3次活检均为阴性 ,行ＣＴ检查 ,诊断为颅底骨纤维组织异常增殖症 ,收住院治疗。查体示一般状况好 ,心肺肝脾无异常 Female patient, 4 6 years old. Because of the left ear bored, with left ear tinnitus in February to consult. Patients with progressive symptoms of exacerbation with headache in the local hospital, see the left ear bone fluid, 2 times tympanic membrane puncture light yellow liquid, check the left nasopharyngeal uplift, three biopsy were negative, the line of CT diagnosis of Skull base bone fibrous dysplasia, admitted to hospital for treatment. Physical examination showed that the general situation is good, no abnormal heart, lung and spleen