酶以前被用作破胶剂。在这些用途中，酶用于清除已使用过而有害无益的化学剂，如钻井液滤饼中或压裂后压裂液中的生物聚合物。目前酶可以用于就地产生油田化学剂，进行酸化、防砂和控水。利用酶产生其它有用的油田化学剂（如矿物、冻胶和树酯等）的工艺也正在研究中。利用酶可 Enzymes used to be used as breaker. In these uses, enzymes are used to remove chemicals that have been used, which are detrimental to use, such as biopolymers in drilling fluid cakes or post-fracturing fracturing fluids. Enzymes can now be used to generate oilfield chemicals in situ for acidification, sand control and water control. Processes using enzymes to generate other useful oil field chemicals such as minerals, jelly and resins are also under investigation. Enzyme can be used