各种应激引起胸腺萎缩、肾上腺肥大早已证实。随着免疫研究进展,注意到应激反应可致患者抗感染、抗肿瘤能力下降,影响免疫功能。胸腺作为中枢性免疫器官对机体免疫(尤其是细胞免疫)有重要影响。关于应激所致胸腺萎缩的发生机制及其对免疫的影响已有一些报道。但周围环境寒冷因素与胸腺、肾上腺cAMP的关系尚未见报道,本文应用大白鼠对周 A variety of stress caused thymus atrophy, adrenal hypertrophy has long been confirmed. With the progress of immunological research, it is noted that stress response can cause patients with anti-infective, anti-tumor ability to decline, affecting immune function. Thymus as a central immune organ on immune (especially cellular immunity) has a significant impact. There have been some reports about the mechanism of stress-induced thymus atrophy and its effect on immunity. However, the relationship between cold factors and thymus and adrenal cAMP has not been reported. In this paper,