东方人饮酒后常出现潮红反应,表现颜面及躯干皮肤泛起红斑,体表温度上升。多有血压上升,心动过速,感头昏、不安、头痛、嗜眠、恶心和心慌。此种反应在黄种人中可达47%～85%。反应迅速、强烈而短暂,一小时左右自行消退。很多实验提示,组胺在这种反应中起的作用。Tan等人曾证明,H_1和H_2受体拮抗剂如扑尔敏、甲腈咪胺等抗组胺药对酒精的潮红反应可起对抗作用。他对两组受试者试验,发现同时给予扑尔敏和甲腈咪胺对阻断反应效果最好,单用甲腈咪胺较差,但比单用扑尔敏好些。他还发现,联合给药后,血酒精浓度比对照组低,故认为抗组胺药对潮 Asians often appear after flushing flushing reaction, the performance of facial and skin erythema caused by trunk, body surface temperature. More blood pressure, tachycardia, dizziness, anxiety, headache, sleepiness, nausea and palpitation. This response in yellow people up to 47% to 85%. Responsive, strong and short-lived, about one hour to resolve itself. Many experiments suggest that histamine plays a role in this reaction. Tan et al. Have demonstrated that H 1 and H 2 receptor antagonists such as chlorpheniramine, cimetidine, and other antihistamines can act as a flush against alcohol flushing. He tested two groups of subjects and found that both chlorpheniramine and cimetidine were most effective in blockade. Monoclopramide was poorer, but better than monochlor alone. He also found that the combination of blood alcohol concentration lower than the control group, it is considered antihistamines on tide