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目的 :医学生感觉寻求与MMPI及单胺氧化酶活性关系的探讨。方法 :以 79名三、四年级医科大学学生为研究对象 ,进行MMPI、感觉寻求及泽克曼 -库赫曼人格问卷测试 ,同时测定血小板MAO活性。结果 :①感觉寻求总分、兴奋与冒险寻求得分、经验寻求得分、冲动性感觉寻求得分均与MMPI中的抑郁项得分呈负相关 (r =- 0 .349,P =0 .0 0 2 ) (r =- 0 .2 3,P =0 .0 4 2 ) (r =- 0 .4 31,P =0 .0 0 0 ) (r =- 0 .2 35 ,P =0 .0 0 3) ;放纵欲望与MMPI中的轻躁狂项得分呈正相关 (r=0 .2 37,P =0 .0 35 )。②冲动性感觉寻求得分与血小板MAO活性呈显著负相关 (r =- 0 .339,P=0 .0 0 9)。结论 :医学生感觉寻求特征与MMPI抑郁呈负相关 ,与轻躁狂呈显著正相关 ;血小板MAO活性可以作为冲动性感觉寻求的生物学标志
Objective: To explore the relationship between medical students’ sensation seeking and MMPI and monoamine oxidase activity. Methods: A total of 79 third and fourth year medical college students were selected as subjects. MMPI, sensory seeking, and Zuckerman-Kuhmann personality test were used to measure platelet MAO activity. Results: ① Feeling seeking score, excitement and adventure seeking score, experience seeking score and impulsive feeling seeking score all had a negative correlation with depression score in MMPI (r = - 0.349, P = 0.002) (r = - 0 .2 3, P = 0 .0 4 2) (r = - 0 .4 31, P = 0 .0 0 0) (r = - 0 .2 35, P = 0 .0 0 3 ). There was a positive correlation between indulgence desire and the score of schizophrenia in MMPI (r = 0.27, P = 0.035). There was a significant negative correlation between impulsive sensory seeking score and platelet MAO activity (r = - 0.339, P = 0.090). CONCLUSION: The seeking characteristics of medical students’ sense of seeking are negatively correlated with MMPI depression and positively correlated with mild mania. The activity of platelet MAO can be used as a biomarker of impulsive sensation