论文部分内容阅读
一、脑肿瘤放射治疗概况放射治疗一直是治疗脑肿瘤的重要手段之一。常规的放射治疗是利用肿瘤细胞与正常脑细胞对放射线“敏感性”的差异,在脑外通过1～2个照射野进行治疗,照射剂量以达到摧毁肿瘤细胞而正常脑细胞又能够耐受为度。这种照射,对某些肿瘤,如:松果体瘤、髓母细胞瘤以及垂体瘤等获得较好疗效,但对某些肿瘤则常因发生严重的放疗反应而终止治疗。对另一些肿瘤,如:脑膜瘤、神经纤维瘤等,常规放疗则无能为力。突出的问题是彻底破坏肿瘤细胞与保护正常脑细胞之间存在的矛盾无法克服。有些学者用多照射野分割照射,据称效果有所改善,但并无大的实质性变化。 1951年Leksell提出立体定向放射外科的
First, the overview of brain tumor radiation therapy Radiation therapy has been an important means of treatment of brain tumors. Conventional radiotherapy is the use of tumor cells and normal brain cells to radiation “sensitivity” difference in the brain by 1 to 2 irradiation field for treatment, irradiation dose to achieve the destruction of tumor cells and normal brain cells can tolerate as degree. This irradiation, for some tumors, such as: pineal tumors, medulloblastoma, and pituitary tumors get better curative effect, but for some tumors are often terminated due to serious radiation response to treatment. For other tumors, such as: meningioma, neurofibroma, etc., conventional radiotherapy can do nothing. Prominent issue is the total destruction of tumor cells and the protection of normal brain cells exist between the contradiction can not be overcome. Some scholars have used multi-radiation field split radiation, the effect is said to have improved, but no major substantive changes. 1951 Leksell proposed stereotactic radiosurgery