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目的 探讨原发心脏弥漫大B细胞淋巴瘤的临床特征、诊疗及预后.方法 报道1例原发心脏弥漫大B细胞淋巴瘤的诊疗结果,结合文献复习,探讨该疾病的临床表现、诊疗及预后.结果 患者,女,27岁,病初表现为反复心悸、呼吸困难,行心脏肿瘤切除术,术后病理示弥漫大B细胞性淋巴瘤,予R-CHOP方案化疗6次,随访至2016年9月患者病情处于稳定状态.结论 原发性心脏弥漫大B细胞淋巴瘤较少见,临床表现无明显特异性,诊断主要依靠病理及免疫组化,治疗仍以化疗为主,但总体预后较差.“,”Objective To report a case of primary cardiac diffuse large B-cell lymphoma to investigate its clinical feature,diagnosis,therapy and prognosis.Methods A case of primary cardiac diffuse large B-cell lymphoma was retrospectively analyzed,and the relevant literatures were reviewed.Results The patient reported recurrent palpitation and dyspnea.Microscopic examination showed diffuse large B-cell lymphoma.The patient was treated with chemotherapy with complete remission and prolonged survival.Conclusion Primary cardiac diffuse large B-cell lymphoma was extremely rare.With non-specific clinical manifestations,the diagnosis was mainly confirmed by histopathological and immunohistochemical staining method.Chemotherapy is an effective treatment,but the patients usually had a poor prognosis.