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目的观察前列地尔与肾康注射液联合治疗老年慢性肾功能衰竭的临床效果。方法选取我院收治的老年慢性肾功能衰竭患者82例,采取数字随机法分成观察组和对照组,对照组采取肾康注射液治疗,观察组在对照组基础上,加用前列地尔治疗,比较两组临床效果。结果两组患者治疗后Cr、Upro、BUN水平均优于治疗前,差异均有统计学意义(均P<0.05)。观察组患者治疗后Cr、Upro、BUN水平优于对照组,差异均有统计学意义(均P<0.05)。观察组用药不良反应发生率7.325%,对照组用药不良反应发生率4.88%,两组患者用药不良反应发生率比较,差异均无统计学意义(均P>0.05)。结论前列地尔与肾康注射液联合治疗老年慢性肾功能衰竭可明显改善患者肾功能,并且较为安全,是优秀的治疗方法之一。
Objective To observe the clinical effects of alprostadil combined with Shenkang injection in the treatment of senile chronic renal failure. Methods 82 elderly patients with chronic renal failure admitted to our hospital were randomly divided into observation group and control group. The control group was treated with Shenkang injection. The observation group was treated with alprostadil, The clinical effects of two groups were compared. Results The levels of Cr, Upro and BUN in both groups were better than those before treatment (all P <0.05). The levels of Cr, Upro and BUN in the observation group were better than those in the control group after treatment (all P <0.05). The incidence of adverse reactions in the observation group was 7.325%, and the incidence of adverse reactions in the control group was 4.88%. There was no significant difference in the incidence of adverse reactions between the two groups (all P> 0.05). Conclusion Alprostadil combined with Shenkang injection in the treatment of senile chronic renal failure can significantly improve renal function and is safer, which is one of the best treatment methods.