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目的分析老年女性膝骨关节炎患者跟骨定量超声与双能X线吸收(DXA)骨密度测定结果之间的相关性。方法以101例老年女性膝骨关节炎患者为研究对象,根据年龄分为3组:﹤65岁38例,65~75岁48例,>75岁15例。均行跟骨定量超声与DXA骨密度检查,分析两者相关性;并以DXA T值评估结果为标准,分析跟骨定量超声相关指标BUA、SOS、T-score和SI对骨质疏松和骨密度降低的诊断效能。结果 >75岁患者的DXA平均T值明显低于﹤65岁患者和65~75岁患者,组间差异有统计学意义(P<0.05);65~75岁患者的BUA、T-score、SI明显低于﹤65岁患者,>75岁患者的BUA、T-score、SI明显低于65~75岁患者,组间差异有统计学意义(P<0.05)。BUA值、T-score、SI与DXA T值具有良好的正相关性(R2=0.3154、0.3207,P<0.05),三者对骨质疏松和骨密度下降均有良好的诊断效能。BUA值、T-score、SI诊断骨质疏松的最佳工作点分别为:BUA=55.205 d B/MHZ,T-score=-2.47,SI=65.635;诊断骨密度降低的最佳工作点分别为:BUA=60.725 d B/MHZ,Tscore=-1.605,SI=79.196。结论跟骨定量超声结果 BUA和T-score与老年女性膝骨关节炎患者骨密度密切相关,对骨质疏松具有预测作用,有望成为其临床筛查工具。
Objective To analyze the correlation between quantitative calcaneal ultrasound and dual-energy X-ray absorptiometry (DXA) in elderly women with knee osteoarthritis. Methods A total of 101 elderly patients with knee osteoarthritis were divided into three groups according to their age: 38 cases were 65 years old, 48 cases were 65-75 years old and 15 cases were> 75 years old. Quantitative ultrasound of calcaneus and DXA BMD were used to analyze the correlation between the two.And the correlation between BUA, SOS and T-score and SI Decreased density of diagnostic efficacy. Results The average T-value of DXA in patients> 75 years old was significantly lower than that in patients <65 years old and 65-75 years old (P <0.05). BUA, T-score, SI Significantly lower BUA, T-score and SI in patients younger than 65 years and 75 years old were significantly lower than those in patients 65-75 years old (P <0.05). There was a positive correlation between BUA, T-score, SI and DXA T values (R2 = 0.3154,0.3207, P <0.05). All three had good diagnostic efficacy for osteoporosis and decreased bone mineral density. The best working points of BUA, T-score and SI in the diagnosis of osteoporosis were BUA = 55.205 d B / MHZ, T-score = -2.47 and SI = 65.635, respectively. The best working points for the diagnosis of osteopenia were : BUA = 60.725 d B / MHZ, Tscore = -1.605, SI = 79.196. Conclusion BUA and T-score results of quantitative calcaneal ultrasound are closely related to bone mineral density in elderly patients with knee osteoarthritis, which may predict osteoporosis and may become a clinical screening tool.