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Cefbuperazone(CBPZ)是头孢菌素类抗生素,对β-内酰胺酶稳定,它对肠细菌、锯杆菌属、产柠檬酸菌属、大肠杆菌、变形菌属和类细菌属等有较强的抗菌作用。曾有CBPZ治疗呼吸系、泌尿系感染的研究报告,对造血系统疾病并发感染的研究不多。本文报告单用CBPZ或与其它抗菌药物联用,治疗这类疾病的临床疗效。病例均为住院治疗的急性骨髓性白血病4例、急性单核细胞性白血病2例、急性淋巴细胞性白血病3例、红白血病1例、慢性骨髓性白血病1例、慢性转急性骨髓性白血病3例、恶性淋巴瘤4例、骨髓异常性增生
Cefbuperazone (CBPZ) is a cephalosporin antibiotic, β-lactamase stable, it is against Enterobacteriaceae, Saurobacterium genus Citrobacter, Escherichia coli, Proteus and other genus bacteria have strong antibacterial effect. There CBPZ treatment of respiratory tract, urinary tract infection in the research report on the hematopoietic system of disease complicated by infection is not much research. This report uses CBPZ alone or in combination with other antibacterials to treat the clinical effects of these conditions. All cases were hospitalized for acute myeloid leukemia in 4 cases, acute monocytic leukemia in 2 cases, acute lymphoblastic leukemia in 3 cases, erythroleukemia in 1 case, chronic myeloid leukemia in 1 case, chronic acute myelogenous leukemia in 3 cases , 4 cases of malignant lymphoma, abnormal bone marrow hyperplasia