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目的:观察有氧运动对冠心病心绞痛患者超敏C反应蛋白(hs-CRP)和白细胞介素6(IL-6)的影响。方法:将60例冠心病心绞痛患者随机分为运动组(30例)与对照组(30例)。对照组患者给予西医常规治疗,运动组在西医常规治疗的基础上配合有氧运动。观察治疗前和治疗6月后患者血清hs-CRP和IL-6水平的变化。结果:治疗前,运动组患者血清hs-CRP和IL-6水平与对照组比较,差异无统计学意义(P>0.05);治疗后,运动组患者血清hs-CRP和IL-6水平均显著低于治疗前和对照组,差异有统计学意义(P<0.01)。结论:有氧运动能够降低冠心病心绞痛患者血清hs-CRP和IL-6的水平。
Objective: To observe the effects of aerobic exercise on high-sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) in patients with coronary heart disease and angina pectoris. Methods: Sixty patients with coronary heart disease and angina pectoris were randomly divided into exercise group (30 cases) and control group (30 cases). Patients in the control group were given routine western medicine treatment. The exercise group cooperated with aerobic exercise on the basis of routine treatment of western medicine. The changes of serum hs-CRP and IL-6 levels before and 6 months after treatment were observed. Results: Before treatment, the levels of serum hs-CRP and IL-6 in exercise group were not significantly different from those in control group (P> 0.05). After treatment, the levels of hs-CRP and IL-6 in exercise group were significantly higher Lower than before treatment and control group, the difference was statistically significant (P <0.01). Conclusion: Aerobic exercise can reduce serum hs-CRP and IL-6 levels in patients with coronary heart disease.