论文部分内容阅读
目的 :探讨肠易激综合征 (IBS)患者肛门直肠运动功能的变化。方法 :对 2 4例腹泻型肠易激综合征患者、14例正常人采用液导法进行直肠肛管压力测定 ,用持续气囊扩张法进行直肠敏感性检测。结果 :腹泻型肠易激综合征患者直肠静息压、直肠外括约肌静息压力、直肠内括约肌静息压力、外括约肌最大缩窄压、内括约肌最大缩窄压 (分别为 2 2± 0 81kPa、8 6 4± 2 7kPa、4 3± 1 4kPa、2 2± 5kPa、9 4± 2 3kPa)与正常组 (9 2± 1 4kPa、5 2± 2 2kPa、1 1± 0 5kPa、2 4± 6kPa、12 9± 4 5kPa)相似(P >0 0 5 )。但直肠最低敏感量、有便意时的气囊容积、便意窘迫时的气囊容积及最大耐受容积 (34± 19ml、74± 2 4ml、12 5±6 4ml和 16 4± 5 2ml)均显著低于正常对照组 (84± 4 8ml、10 4± 5 2ml、2 0 4± 6 9ml、2 5 4± 74ml) (P <0 0 5 )。结论 :IBS患者症状的产生可能与直肠肛管的机械压力无关 ,直肠高敏感性可能在IBS患者肠道症状的产生重要作用
Objective: To investigate the changes of anorectal motor function in patients with irritable bowel syndrome (IBS). Methods: Twenty-four cases of diarrhea-predominant irritable bowel syndrome and 14 normal controls were enrolled in this study. The rectal analgesia was measured by liquid-conduction method and rectal sensitivity was measured by continuous balloon dilatation. Results: Resting pressure, rectal sphincter rest pressure, rectal sphincter rest pressure, maxillary constriction sphincter pressure and maxillary sphincter constriction pressure were 22 ± 0 81 kPa , 8 6 4 ± 2 7kPa, 4 3 ± 1 4kPa, 2 2 ± 5kPa, 9 4 ± 2 3kPa) and normal group (9 2 ± 1 4kPa, 5 2 ± 2 2kPa, 1 1 ± 0 5kPa, 2 4 ± 6kPa, 12 9 ± 4 5kPa) (P> 0.05). However, the lowest rectal sensitivities, the volume of air sacs at the time of delivery, the volume of air sacs at the time of distress, and the maximum tolerated volume (34 ± 19 ml, 74 ± 24 ml, 125 ± 64 ml, and 164 ± 52 ml) Normal control group (84 ± 48ml, 104 ± 52ml, 204 ± 69ml, 254 ± 74ml) (P <0 05). CONCLUSION: Symptoms of IBS patients may not be related to the mechanical pressure of the rectal anal canal. High rectal sensitivity may play an important role in the development of intestinal symptoms in IBS patients