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原发性小血管炎是一种严重的多系统性疾病,临床表现复杂多样,极易误诊或漏诊。国外报道较多,国内在生前确诊者极少,现将笔者所见1例并结合国内外有关新进展报告如下。患者男,57岁,因间断咳嗽、咳痰3年,浮肿2年,恶心、呕吐3月入院。患者3年前出现咳嗽、咳痰,用抗菌素治疗不见好转,给予地塞米松5mg/日静注,3天后症状缓解。二年前又出现发热、咳嗽、气喘,换用多种抗菌素治疗无效,并出现眼睑浮肿、恶心呕吐,实验室检查示急性肾衰。予强的松及环磷酰胺治疗,并行2次血
Primary small vessel vasculitis is a serious multi-system disease, complex and diverse clinical manifestations, easily misdiagnosed or missed diagnosis. There are more foreign reports and fewer domestic confirmed cases before their death. Now I report 1 case and report on new developments both at home and abroad. Male, 57 years old, died of intermittent cough, expectoration for 3 years, edema for 2 years, and nausea and vomiting were admitted to hospital in March. 3 years ago, patients with cough, expectoration, treatment with antibiotics did not improve, give dexamethasone 5mg / day intravenous injection, 3 days after the symptoms were relieved. Two years ago there fever, cough, asthma, for a variety of antibiotic treatment ineffective, and eyelid edema, nausea and vomiting, laboratory tests showed acute renal failure. To prednisone and cyclophosphamide treatment, parallel blood 2 times