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血管内皮细胞除具有屏障功能外还可以产生和分泌十余种生物活性物质,可认为是机体最大的内分泌腺.生理功能包括:调节血管的舒张和收缩;提供一个抗血栓形成及抗白细胞粘附的表面;控制平滑肌细胞增殖、参与局部止血及炎症和免疫反应等作用.舒张功能受损为主要表现的血管内皮功能障碍在心血管疾病中起着重要的作用,文中就内皮功能障碍的检测与防治做一综述.
In addition to having a barrier function, vascular endothelial cells can produce and secrete more than ten kinds of bioactive substances, which can be considered as the body’s largest endocrine glands. Physiological functions include: regulating blood vessel relaxation and contraction; providing an antithrombotic and anti-leukocyte adhesion Control of smooth muscle cell proliferation, involved in local hemostasis and inflammation and immune response, etc .. Vascular endothelial dysfunction as the main manifestation of diastolic dysfunction play an important role in cardiovascular disease, the detection and prevention and treatment of endothelial dysfunction Do a review.