巨细胞病毒(CMV)是先天性及围产期病毒感染最常见的原因.其病率远远超过先天风疹,但直到最近,对其影响仍多忽视,近来实验室诊断技术的进步及许多周密的前瞻性研究已有助于阐明CMV感染的自然史、对胎儿的影响、多期感染可能造成的远期后遗症以及婴幼儿期感染的来源.许多研究表明约1%(0.5～4%)的婴 Cytomegalovirus (CMV) is the most common cause of congenital and perinatal viral infections and its prevalence is much higher than that of congenital rubella, but until recently its effects were still largely overlooked. Recent advances in laboratory diagnostic techniques and many well- Of prospective studies have helped to elucidate the natural history of CMV infection, its effects on the fetus, long-term sequelae of multiple infections, and the sources of infection in infants and toddlers. Many studies have shown that about 1% (0.5-4%) of infant