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本文就干扰素(IFN)治疗慢性丙肝(CHC)的依据、用法、病例选择、疗效评价、复发问题及今后研究方向等方面简要综述。 1 IFN治疗丙肝的依据 许多小样本,对照研究证实IFN治疗可抑制丙肝病毒(HCV)相关肝病的活动性,多数病情缓解。IFN3～5Mu,每周3次给药后,40％～70％病人出现血清生化反应,转氨酶水平降低。有研究表明,这种血清生化改善与肝组织学改
This article briefly reviews the basis, usage, case selection, efficacy evaluation, recurrence and future research direction of interferon (IFN) in the treatment of chronic hepatitis C (CHC). 1 IFN treatment of hepatitis C based on many small samples, the control study confirmed that IFN treatment can inhibit the activity of hepatitis C virus (HCV) -related liver disease, most of the remission. IFN3 ~ 5Mu, three times a week after administration, 40% to 70% of patients with serum biochemical reactions, aminotransferase levels decreased. Studies have shown that this serum biochemical improvement and liver histology change