目前只有一种经美国食品和药物管理局批准的乙型脑炎疫苗 ,即日本 BIKEN公司生产的鼠脑纯化灭活疫苗。尽管日本报道其安全性很好 ,但自 1986年以来美国、欧洲和澳大利亚接种者中副反应达 10 %～ 2 0 % ,如 :发热、头痛 ,局部红肿 ,并有较多的变态反应报告 ,如荨麻疹、面部血管 Currently, there is only one encephalitis vaccine approved by the U.S. Food and Drug Administration, a rat brain-purified inactivated vaccine produced by BIKEN, Japan. Although Japan reported its safety, the side effects of vaccination in the United States, Europe and Australia since 1986 were 10% to 20%, such as fever, headache, local redness, and more allergic reactions, Such as urticaria, facial blood vessels