例1、男,4个月。因面色苍黄20余天入院。患儿20余天前无明显诱因出现面色苍黄,并逐渐加重,无发热,无鼻衄,无齿龈出血,无便血,无排浓茶样小便。曾在当地医院诊治,病情无好转而来我院求医。患儿无苯等化学毒物接触史,无放射线接触史,无服用氯霉素史;父母均体健,非近亲婚配,家族中及当地人群中无类似病史,PE:神清、面色苍黄、呈重度 Example 1, male, 4 months. Due to looking pale yellow more than 20 days admitted to hospital. Children with more than 20 days no obvious incentive to appear pale yellow, and gradually increased, no fever, no nose and throat, no bleeding gums, no blood in the stool, no row of strong tea-like urine. In the local hospital treatment, no improvement in our condition to seek medical treatment in our hospital. Children with no history of exposure to benzene and other chemical toxicants, no history of radiation exposure, no history of taking chloramphenicol; parents are healthy, non-relatives marriage, no similar family history and local population history, PE: Shen Qing, pale yellow, was Severe