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目的探讨绝经后泌尿系感染反复发作应用小剂量雌激素预防的临床疗效。方法选取本院收治的98例绝经后泌尿系感染反复发作患者,随机将其分为观察组和对照组,各49例,给予对照组患者常规抗生素治疗,观察组则在对照组治疗的基础上加行小剂量雌激素治疗,并对两组患者的治疗总有效率、复发率、治疗前后阴道健康评分及复发性阴道炎症评分进行对比。结果观察组患者的治疗总有效率、复发率、治疗后阴道健康评分及复发性阴道炎症评分均明显优于对照组(P<0.05)。结论在常规抗生素治疗的基础上对绝经后泌尿系感染反复发作患者加行小剂量雌激素治疗可有效的提高治疗效果,减少患者复发,值得临床推广和应用。
Objective To investigate the clinical efficacy of estrogen prophylaxis in recurrent urinary tract infection after menopause. Methods A total of 98 patients with recurrent urinary tract infection in our hospital were selected and randomly divided into observation group and control group, 49 cases in each group. The patients in the control group were given conventional antibiotics. On the basis of the control group, Plus low-dose estrogen treatment, and the two groups of patients with total effective rate, relapse rate, vaginal health score before and after treatment and recurrent vaginal inflammation score comparison. Results The total effective rate, relapse rate, post-treatment vaginal health score and recurrent vaginal inflammation score in the observation group were significantly better than those in the control group (P <0.05). Conclusion On the basis of conventional antibiotic treatment, repeated treatment of post-menopausal urinary tract infection in patients with small doses of estrogen therapy can effectively improve the treatment effect and reduce the recurrence of patients, worthy of clinical promotion and application.