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目的:探讨妊娠合并糖尿病的孕期管理、及时诊断和规范化治疗与母婴结局的关系。方法:回顾性分析我院1995年1月～2005年1月间具有两次妊娠合并糖尿病的妊娠分娩史的13例患者的临床资料,使其自身作为对照,比较此次妊娠和前次妊娠的母婴结局,如孕妇并发症包括早产、羊水过多、感染、死胎,并发糖尿病酮症酸中毒和子痫前期,围产儿病率包括巨大儿、新生儿畸形、新生儿窒息、新生儿低血糖、新生儿呼吸窘迫综合征和围产儿死亡等。结果:26次妊娠中,24次妊娠合并糖尿病的诊断时间为20周后,前次妊娠孕妇并发症和围产儿病率显著高于此次妊娠(P<0.05);未诊治者或者血糖控制不满意者围产儿病率显著高于血糖控制满意或尚可者(P<0.01)。结论:规范妊娠合并糖尿病的孕期管理,及时发现糖尿病孕妇并使之血糖控制满意可明显改善妊娠合并糖尿病患者的母婴预后。
Objective: To investigate the pregnancy management of pregnancy complicated with diabetes, timely diagnosis and standardization of treatment and the relationship between mother and baby outcomes. Methods: A retrospective analysis of our hospital from January 1995 to January 2005 with two gestational diabetes mellitus history of labor and delivery of the clinical data of 13 patients, making itself as a control, comparing the pregnancy and previous pregnancy Maternal and infant outcomes such as maternal complications such as preterm birth, polyhydramnios, infections, stillbirths, diabetic ketoacidosis and preeclampsia, perinatal morbidity include macrosomia, neonatal malformation, neonatal asphyxia, neonatal hypoglycemia, Neonatal respiratory distress syndrome and perinatal death and so on. Results: In 26 pregnancies, the diagnosis of 24 pregnancies with diabetes mellitus was 20 weeks later. The incidence of complications and perinatal morbidity in the previous pregnancy were significantly higher than those in the second trimester (P <0.05) Satisfaction with perinatal morbidity was significantly higher than that of blood glucose control or acceptable (P <0.01). CONCLUSION: Regulating pregnancy management during pregnancy with diabetes mellitus and timely finding pregnant women with diabetes and satisfying their blood sugar control can significantly improve the maternal and infant prognosis in patients with pregnancy complicated with diabetes.